A recurrent sequencing artifact on Illumina sequencers with two-color fluorescent dye chemistry and its impact on somatic variant detection
Abstract Background The sequencing-by-synthesis technology by Illumina, Inc. enables efficient and scalable readouts of mutations from genomic data. To enhance sequencing speed and efficiency, Illumina has shifted from the four-color base calling chemistry of the HiSeq series to a two-color fluoresc...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BMC
2026-04-01
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| سلاسل: | Genome Biology |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s13059-026-04081-3 |
| الوسوم: |
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