Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.

The mitochondrial beta-oxidation system is one of the central metabolic pathways of energy metabolism in mammals. Enzyme defects in this pathway cause fatty acid oxidation disorders. To elucidate the role of 2,4-dienoyl-CoA reductase (DECR) as an auxiliary enzyme in the mitochondrial beta-oxidation...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ilkka J Miinalainen, Werner Schmitz, Anne Huotari, Kaija J Autio, Raija Soininen, Emiel Ver Loren van Themaat, Myriam Baes, Karl-Heinz Herzig, Ernst Conzelmann, J Kalervo Hiltunen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2009-07-01
coleção:	PLoS Genetics
Acesso em linha:	http://europepmc.org/articles/PMC2697383?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!