Metabolic Engineering to Improve Docosahexaenoic Acid Production in Marine Protist Aurantiochytrium sp. by Disrupting 2,4-Dienoyl-CoA Reductase

Docosahexaenoic acid (DHA) has attracted attention from researchers because of its pharmacological and nutritional importance. Currently, DHA production costs are high due to fermentation inefficiency; however, improving DHA yield by metabolic engineering in thraustochytrids is one approach to reduc...

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Principais autores:	Shitong Liang, Xuewei Yang, Xingyu Zhu, Muhammad Ibrar, Liangxu Liu, Siting Li, Xia Li, Tian Tian, Shuangfei Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-07-01
coleção:	Frontiers in Marine Science
Assuntos:	omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) PUFA beta-oxidation 2,4-dienoyl-CoA reductase (DECR) Aurantiochytrium sp.
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmars.2022.939716/full
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