Grasping the duality of fumonisins versus ceramide synthases: a computational approach to study their role as inhibitors and substrates from a mechanistic standpoint

Fumonisins are Fusarium mycotoxins contaminating cereals worldwide. Fumonisin B1 (FB1) and its hydrolysed form (HFB1) are among those of most concern to food safety. They chemically resemble sphingoid bases and may alter the sphingolipid rheostat by inhibiting the ceramide synthases (CerSs). They ma...

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מידע ביבליוגרפי

Principais autores:	Florinda Perugino, Lorenzo Pedroni, Gianni Galaverna, Chiara Dall’Asta, Luca Dellafiora
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2025-08-01
סדרה:	Heliyon
נושאים:	Fumonisin B1 Mycotoxins Molecular modelling Ceramide synthases Mechanisms of action
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2405844025021140
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