Grasping the duality of fumonisins versus ceramide synthases: a computational approach to study their role as inhibitors and substrates from a mechanistic standpoint
Fumonisins are Fusarium mycotoxins contaminating cereals worldwide. Fumonisin B1 (FB1) and its hydrolysed form (HFB1) are among those of most concern to food safety. They chemically resemble sphingoid bases and may alter the sphingolipid rheostat by inhibiting the ceramide synthases (CerSs). They ma...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2025-08-01
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| coleção: | Heliyon |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2405844025021140 |
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