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Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.

The characteristic neuropathological changes associated with Alzheimer's disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...

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Detalhes bibliográficos
Principais autores: Alex E Roher, David H Cribbs, Ronald C Kim, Chera L Maarouf, Charisse M Whiteside, Tyler A Kokjohn, Ian D Daugs, Elizabeth Head, Carolyn Liebsack, Geidy Serrano, Christine Belden, Marwan N Sabbagh, Thomas G Beach
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3605408?pdf=render
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