Nucleoporin Nsp1 surveils the phase state of FG-Nups

Summary: Transport through the nuclear pore complex (NPC) relies on intrinsically disordered FG-nucleoporins (FG-Nups) forming a selective barrier. Away from the NPC, FG-Nups readily form condensates and aggregates, and we address how this behavior is surveilled in cells. FG-Nups, including Nsp1, to...

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Principais autores:	Tegan A. Otto, Tessa Bergsma, Maurice Dekker, Sara N. Mouton, Paola Gallardo, Justina C. Wolters, Anton Steen, Patrick R. Onck, Liesbeth M. Veenhoff
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-10-01
叢編:	Cell Reports
主題:	CP: Molecular biology
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211124724011446
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