Predictive biomarkers for the efficacy of PARP inhibitors in ovarian cancer: an updated systematic review

Abstract Background PARP inhibitors are effective in treating ovarian cancer, especially for BRCA1/2 pathogenic variant carriers and those with HRD (homologous recombination deficiency). Concerns over toxicity and costs have led to the search for predictive biomarkers. We present an updated systemat...

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Hlavní autoři:	Ying-Wen Wang, Isaac Allen, Gabriel Funingana, Marc Tischkowitz, Yvonne Walburga Joko-Fru
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-03-01
Edice:	BJC Reports
On-line přístup:	https://doi.org/10.1038/s44276-025-00122-9
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