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Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and management

Ovarian cancer patients with homologous recombination deficiencies exhibit specific clinical behaviors, and improved responses to treatments, such as platinum-based chemotherapy and poly (ADP-ribose) polymerase (PARP) inhibitors, have been observed. Germline mutations in the BRCA 1/2 genes are the m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Renata Rodrigues da Cunha Colombo Bonadio, Rodrigo Nogueira Fogace, Vanessa Costa Miranda, Maria del Pilar Estevez Diz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier España 2018-08-01
Cyfres:Clinics
Pynciau:
Mynediad Ar-lein:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000200308&lng=en&tlng=en
Tagiau: Ychwanegu Tag
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