The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia
Chronic lymphocytic leukemia is marked by profound defects in T-cell function. Programmed death-1 is a receptor involved in tumor-mediated immunosuppression through binding of the PD-L1 ligand. Multiparametric flow cytometry and immunohistochemistry were used to study PD-1/PD-L1 expression. Function...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2013-06-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/6698 |
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