The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy

T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory checkpoint receptor that negatively regulates Tcell responses. CD226 competes with TIGIT for binding to the CD155 ligand, delivering a positive signal to the T cell. Here we studied the expression of TIGIT and CD226 in a cohort...

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Autors principals:	Francesca Arruga, Marta Rubin, Despoina Papazoglou, Andrea Iannello, Nikolaos Ioannou, Riccardo Moia, Davide Rossi, Gianluca Gaidano, Marta Coscia, Luca Laurenti, Giovanni D’Arena, John N. Allan, Richard R. Furman, Tiziana Vaisitti, Alan G. Ramsay, Silvia Deaglio
Format:	Artigo
Idioma:	Inglês
Publicat:	Ferrata Storti Foundation 2023-01-01
Col·lecció:	Haematologica
Accés en línia:	https://haematologica.org/article/view/10940
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