Código QR (código de barras bidimensional)

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Abstract Deposition of amyloid beta (Aβ) into plaques is a major hallmark of Alzheimer’s disease (AD). Different amyloid precursor protein (APP) mutations cause early-onset AD by altering the production or aggregation properties of Aβ. We recently identified the Uppsala APP mutation (APPUpp), which...

Fuld beskrivelse

Na minha lista:
Principais autores: María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R. Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L. Spires-Jones, Lars Lannfelt, Lars N. G. Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-02-01
Serier:Acta Neuropathologica Communications
Fag:
Alzheimer’s disease (AD)
Amyloid precursor protein (APP)
Amyloid-beta (Aβ)
PET imaging
Microglia
Astrocytes
Online adgang:https://doi.org/10.1186/s40478-024-01734-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker