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SETDB1 promotes gastric cancer progression via UPR and mTOR pathway

Abstract SET Domain Bifurcated histone lysine methyltransferase 1 (SETDB1), a histone H3K9 methyltransferase, is frequently overexpressed in multiple malignancies, including gastric cancer (GC). However, its molecular functions and regulatory mechanisms in GC progression remain poorly defined. Here,...

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Bibliografische gegevens
Hoofdauteurs: Jing Qiao, Shijie Lin, Yeju Li, Xiaoyang Yue, Yanyan Liu, Huajian Tian, Jianshuang Li, Junyang Tan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2026-04-01
Reeks:Cancer Cell International
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Online toegang:https://doi.org/10.1186/s12935-026-04296-1
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