SETDB1 promotes gastric cancer progression via UPR and mTOR pathway

Abstract SET Domain Bifurcated histone lysine methyltransferase 1 (SETDB1), a histone H3K9 methyltransferase, is frequently overexpressed in multiple malignancies, including gastric cancer (GC). However, its molecular functions and regulatory mechanisms in GC progression remain poorly defined. Here,...

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Bibliografiske detaljer

Principais autores:	Jing Qiao, Shijie Lin, Yeju Li, Xiaoyang Yue, Yanyan Liu, Huajian Tian, Jianshuang Li, Junyang Tan
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-04-01
Serier:	Cancer Cell International
Fag:	Gastric cancer SETDB1 Histone H3K9 methyltransferase Unfolded protein response MTOR
Online adgang:	https://doi.org/10.1186/s12935-026-04296-1
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