Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations

Microbes have shown a remarkable ability in evading the killing actions of antimicrobial agents, such that treatment of bacterial infections represents once more an urgent global challenge. Understanding the initial bacterial response to antimicrobials may reveal intrinsic tolerance mechanisms to an...

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Autors principals:	Mattia Zampieri, Michael Zimmermann, Manfred Claassen, Uwe Sauer
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2017-05-01
Col·lecció:	Cell Reports
Matèries:	E. coli antibiotic response metabolomics antibiotic tolerance dTDP-rhamnose ammonium imbalance quinolones chloramphenicol
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124717304618
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