Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations

Microbes have shown a remarkable ability in evading the killing actions of antimicrobial agents, such that treatment of bacterial infections represents once more an urgent global challenge. Understanding the initial bacterial response to antimicrobials may reveal intrinsic tolerance mechanisms to an...

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Detalhes bibliográficos

Principais autores:	Mattia Zampieri, Michael Zimmermann, Manfred Claassen, Uwe Sauer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-05-01
coleção:	Cell Reports
Assuntos:	E. coli antibiotic response metabolomics antibiotic tolerance dTDP-rhamnose ammonium imbalance quinolones chloramphenicol
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124717304618
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