Development and characterization of a human papillomavirus-based nanoparticle carrier for heterologous vaccine antigens

Abstract The display of a repetitive array of antigens on the surface of nanoparticles has been shown to effectively trigger the activation of cognate B cells and to increase humoral immune responses. Building on extensive knowledge from the development and clinical use of virus-like particle (VLP)...

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Ngā kaituhi matua:	Yu Wang, Nils Bartelsen, Philipp Arnold, Sandra Mueller-Schmucker, Christoph Weingärtner, Jannis Beutel, Jutta Eichler, Vladimir Temchura, Dominik Damm, Klaus Überla
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2025-09-01
Rangatū:	Scientific Reports
Ngā marau:	Virus-like particle (VLP) T helper nanoparticles HIV vacciner Env trimer B cell activation Humoral immune response
Urunga tuihono:	https://doi.org/10.1038/s41598-025-19009-3
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!