Impaired mitochondrial ketone body oxidation in insulin resistant statesResearch in context

Summary: Background: Reduced mitochondrial respiratory function has been implicated in metabolic disorders like type 2 diabetes (T2D), obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD), which are tightly linked to insulin resistance and impaired metabolic flexibility. Ho...

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Autors principals:	Elric Zweck, Sarah Piel, Johannes W. Schmidt, Daniel Scheiber, Martin Schön, Sabine Kahl, Volker Burkart, Bedair Dewidar, Ricarda Remus, Alexandra Chadt, Hadi Al-Hasani, Lucia Mastrototaro, Hug Aubin, Udo Boeken, Artur Lichtenberg, Jörg Distler, Amin Polzin, Malte Kelm, Ralf Westenfeld, Robert Wagner, Patrick Schrauwen, Julia Szendroedi, Michael Roden, Cesare Granata
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-12-01
Col·lecció:	EBioMedicine
Matèries:	Mitochondrial respiration Ketone bodies Diabetes mellitus Obesity MASLD
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2352396425004517
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