Cortical Thinning of Motor and Non-Motor Brain Regions Enables Diagnosis of Amyotrophic Lateral Sclerosis and Supports Distinction between Upper- and Lower-Motoneuron Phenotypes

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder clinically characterized by muscle atrophy and progressive paralysis. In addition to the classical ALS affecting both the upper and lower motoneurons (UMN and LMN), other subtypes with the predominant (or even exclusive)...

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Detalhes bibliográficos

Principais autores:	Stefano Ferrea, Frederick Junker, Mira Korth, Kai Gruhn, Torsten Grehl, Tobias Schmidt-Wilcke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-09-01
coleção:	Biomedicines
Assuntos:	cortical thinning multivariate analysis amyotrophic lateral sclerosis upper motoneuron lower motoneuron
Acesso em linha:	https://www.mdpi.com/2227-9059/9/9/1195
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