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Cortical Thinning of Motor and Non-Motor Brain Regions Enables Diagnosis of Amyotrophic Lateral Sclerosis and Supports Distinction between Upper- and Lower-Motoneuron Phenotypes

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder clinically characterized by muscle atrophy and progressive paralysis. In addition to the classical ALS affecting both the upper and lower motoneurons (UMN and LMN), other subtypes with the predominant (or even exclusive)...

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Principais autores: Stefano Ferrea, Frederick Junker, Mira Korth, Kai Gruhn, Torsten Grehl, Tobias Schmidt-Wilcke
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-09-01
סדרה:Biomedicines
נושאים:
cortical thinning
multivariate analysis
amyotrophic lateral sclerosis
upper motoneuron
lower motoneuron
גישה מקוונת:https://www.mdpi.com/2227-9059/9/9/1195
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