Comparative effectiveness of Tenecteplase and Alteplase for ischemic stroke: real-world data from a stroke center

Abstract Background Tenecteplase (TNK) and Alteplase (rt-PA) are intravenous thrombolytics used in acute ischemic stroke (AIS). While Alteplase has long been the standard of care, TNK is now also approved for AIS by both the EMA and FDA. Its single-bolus administration and favorable pharmacokinetics...

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Autors principals:	Toska Maxhuni, Francesca Culaj, Merve-Melis Sayar, Priyanka Böttger, Samra Hamzic, Stefan T. Gerner, Tobias Braun, Maxime Viard, Martin Juenemann, Heidrun H. Krämer, Omar AlHaj Omar
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-01-01
Col·lecció:	BMC Neurology
Matèries:	Acute ischemic stroke Tenecteplase Alteplase Intravenous thrombolysis Door-to-needle time
Accés en línia:	https://doi.org/10.1186/s12883-026-04655-5
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