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Tenecteplase versus alteplase in bridging therapy in patients with large vessel occlusion stroke: a meta-analysis

BackgroundCurrently, for patients with large-vessel occlusion (LVO) strokes, the standard treatment approach involves using alteplase (ALT) as a bridge to endovascular mechanical thrombectomy (MT). Tenecteplase (TNK) is a novel fibrinolytic agent. Our research is focused on evaluating and comparing...

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Principais autores: Xiaohan Zhang, Min Tao, Tian Wang, Rongxin He, Lingwan Yan, Xiaozuo Lin, Pingkai Wang, Yinan Zeng, Jipeng Yu, Hongxia Liu, Man Luo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Neurology
Fag:
acute ischemic stroke
tenecteplase
alteplase
intravenous thrombolysis
mechanical thrombectomy
Online adgang:https://www.frontiersin.org/articles/10.3389/fneur.2025.1661357/full
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