A snake venom-analog peptide that inhibits SARS-CoV-2 and papain-like protease displays antithrombotic activity in mice arterial thrombosis model, without interfering with bleeding time
Highlights • Venom-analog peptide, (p-BthTX-I)2K, inhibits SARS-CoV-2 infection and papain-like protease. • Bothropstoxin-I-derived peptide analog shows antithrombotic action. • (p-BthTX-I)2K prolonged aPTT and PT by blocking kallikrein and factor Xa. • Venom-analog peptide, (p-BthTX-I)2K, shows ant...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
BMC
2023-01-01
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| Sraith: | Thrombosis Journal |
| Ábhair: | |
| Rochtain ar líne: | https://doi.org/10.1186/s12959-022-00436-5 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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