Protein Misfolding and Aggregation as a Mechanistic Link Between Chronic Pain and Neurodegenerative Diseases

Chronic pain, defined by persistent pain beyond normal healing time, is a pervasive and debilitating condition affecting up to 30–50% of adults globally. In parallel, neurodegenerative diseases (NDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS)...

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Autori principali:	Nebojsa Brezic, Strahinja Gligorevic, Aleksandar Sic, Nebojsa Nick Knezevic
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-04-01
Serie:	Current Issues in Molecular Biology
Soggetti:	chronic pain neurodegenerative diseases protein misfolding protein aggregation unfolded protein response endoplasmic reticulum stress
Accesso online:	https://www.mdpi.com/1467-3045/47/4/259
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