Aiolos restricts the generation of antigen-inexperienced, virtual memory CD8+ T cells in mice

Abstract CD8+ virtual memory T (TVM) cells rapidly respond to infection via antigen-independent bystander effector functions. While it is recognized that TVM cells arise independently of foreign antigen encounter, the mechanisms governing their development are not fully understood. Here, we identify...

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Autori principali:	Srijana Pokhrel, Gayathri Dileepan, Melissa R. Leonard, Robert T. Warren, Mariam Salem, Allison J. Yacapraro, Qiaoke Gong, Devin M. Jones, Jasmine A. Tuazon, Kaitlin A. Read, Jacob S. Yount, Gang Xin, Adriana Forero, Hazem E. Ghoneim, Patrick L. Collins, Emily A. Hemann, Kenneth J. Oestreich
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-12-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-025-67540-8
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