ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNβ/λ expression and promotes ZIKV persistence

ABSTRACT Zika virus (ZIKV) is a mosquito-borne Flavivirus that persistently infects patients; enters protected brain, placental, and testicular compartments; is sexually transmitted; and causes fetal microcephaly in utero. ZIKV persistently infects human brain microvascular endothelial cells (hBMECs...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	William R. Schutt, Jonas N. Conde, Megan C. Mladinich, Grace E. Himmler, Erich R. Mackow
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2023-10-01
Цуврал:	mBio
Нөхцлүүд:	Zika virus tristetraprolin endothelial cells Sertoli cells interferon regulation persistence
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/mbio.01742-23
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!