Proteolysis during tumor cell extravasation in vitro: metalloproteinase involvement across tumor cell types.

To test if proteolysis is involved in tumor cell extravasation, we developed an in vitro model where tumor cells cross an endothelial monolayer cultured on a basement membrane. Using this model we classified the ability of the cells to transmigrate through the endothelial cell barrier onto the under...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Evelyn B Voura, Jane L English, Hoi-Ying E Yu, Andrew T Ho, Patrick Subarsky, Richard P Hill, Carlo V Hojilla, Rama Khokha
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC3806793?pdf=render
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!