Proteolysis during tumor cell extravasation in vitro: metalloproteinase involvement across tumor cell types.

To test if proteolysis is involved in tumor cell extravasation, we developed an in vitro model where tumor cells cross an endothelial monolayer cultured on a basement membrane. Using this model we classified the ability of the cells to transmigrate through the endothelial cell barrier onto the under...

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Detalles Bibliográficos

Autores principales:	Evelyn B Voura, Jane L English, Hoi-Ying E Yu, Andrew T Ho, Patrick Subarsky, Richard P Hill, Carlo V Hojilla, Rama Khokha
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2013-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3806793?pdf=render
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