miR-374-5p inhibits osteogenesis by targeting PTEN/PI3K/AKT signaling pathway
Abstract Purpose This study aims to evaluate the effects of miR-374-5p on osteogenesis in rat osteoblasts, validate its target on PTEN, and explore its role in the PTEN/PI3K/AKT signaling pathway during osteoblast differentiation. Methods We transfected 293T cells with miR-374-5p mimics and inhibito...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2025-03-01
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| Colecção: | Journal of Orthopaedic Surgery and Research |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13018-025-05670-x |
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