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MiR-124-3p mediates gastric cancer cell ferroptosis induced by an anti-cancer drug polyphyllin I

Background: Ferroptosis is an emerging type of regulated cell death and associated with antitumoral therapy, while some microRNAs have been shown to regulate the tumorigenesis and cancer progression. Meanwhile, polyphyllin I (PPI) has exhibited antitumoral effects by promoting cancer cell apoptosis...

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Autores principales: Fang Zheng, Jian-Can Bi, Yu-Yan Wei, Yeshu Wang, Qunfang Zhang, Chun-Ling Liang, Jianwei Wu, Zhenhua Dai
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2023-11-01
Colección:Frontiers in Pharmacology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fphar.2023.1285799/full
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