Polyphyllin II inhibits thyroid cancer cell growth by simultaneously inhibiting glycolysis and oxidative phosphorylation

Thyroid cancer is the most common malignancy of the endocrine system, and effective treatments for metastatic disease are still lacking. Targeting both glycolysis and oxidative phosphorylation (OXPHOS) simultaneously represents a novel approach to cancer therapy. While polyphyllin has been shown to...

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Auteurs principaux:	Sun Jianwei, Ding Ding, Xiang Qian, Zheng Mengyang, Dai Mingming
Format:	Artigo
Langue:	Inglês
Publié:	De Gruyter 2025-10-01
Collection:	Open Medicine
Sujets:	polyphyllin glycolysis oxidative phosphorylation proliferation invasion migration apoptosis
Accès en ligne:	https://doi.org/10.1515/med-2025-1286
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