MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function
Abstract Background Foxp3+CD4+ regulatory T cells (Treg) constitutes a key event in autoimmune diseases. STAT5b is the critical link between the IL-2/15 and FOXP3, the master regulator of Treg cells. Methods The CD3+T cell and Foxp3+CD4+ regulatory T cells were overexpressioned or knockdown MKL-1 an...
Збережено в:
| Автори: | , , , , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2020-07-01
|
| Серія: | Cell Communication and Signaling |
| Предмети: | |
| Онлайн доступ: | http://link.springer.com/article/10.1186/s12964-020-00574-1 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|