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Kaempferol activates chloride secretion via the cAMP/PKA signaling pathway and expression of CFTR in T84 cells

Kaempferol is a flavonol identified as the most potent activator of chloride (Cl−) secretion among other flavonoids in airway epithelial cells. This study aimed to investigate the cellular mechanisms by which kaempferol stimulates Cl− secretion in the T84 human colon carcinoma cell line by Ussing ch...

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Principais autores: Janjira Thaweewattanodom, Chatsri Deachapunya, Sutthasinee Poonyachoti
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-09-01
Serier:Frontiers in Pharmacology
Fag:
kaempferol
T84 cells
Cl− secretion
short-circuit current
apical Cl− current
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1401273/full
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