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Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity

Maintaining the excitability of neurons and circuits is fundamental for healthy brain functions. The global compensatory increase in excitatory synaptic strength, in response to decreased activity, is one of the main homeostatic mechanisms responsible for such regulation. This type of plasticity has...

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Autori principali: Federica Cordella, Laura Ferrucci, Chiara D’Antoni, Silvia Ghirga, Carlo Brighi, Alessandro Soloperto, Ylenia Gigante, Davide Ragozzino, Paola Bezzi, Silvia Di Angelantonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-11-01
Serie:Life
Soggetti:
neurons
plasticity
iPSC
astrocytes
action potential
calcium imaging
Accesso online:https://www.mdpi.com/2075-1729/12/11/1884
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