A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes.

Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making it...

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Detalhes bibliográficos

Principais autores:	Rory Johnson, Nadine Richter, Gireesh K Bogu, Akshay Bhinge, Siaw Wei Teng, Siew Hua Choo, Lise O Andrieux, Cinzia de Benedictis, Ralf Jauch, Lawrence W Stanton
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS Genetics
Acesso em linha:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002624&type=printable
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