A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes.
Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making it...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2012-01-01
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| Schriftenreihe: | PLoS Genetics |
| Online-Zugang: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002624&type=printable |
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