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NANOG is required to establish the competence for germ-layer differentiation in the basal tetrapod axolotl.

Pluripotency defines the unlimited potential of individual cells of vertebrate embryos, from which all adult somatic cells and germ cells are derived. Understanding how the programming of pluripotency evolved has been obscured in part by a lack of data from lower vertebrates; in model systems such a...

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Autors principals: Luke A Simpson, Darren Crowley, Teri Forey, Helena Acosta, Zoltan Ferjentsik, Jodie Chatfield, Alexander Payne, Benjamin S Simpson, Catherine Redwood, James E Dixon, Nadine Holmes, Fei Sang, Ramiro Alberio, Matthew Loose, Andrew D Johnson
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2023-06-01
Col·lecció:PLoS Biology
Accés en línia:https://doi.org/10.1371/journal.pbio.3002121
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