Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression.
Under RNA virus infection, retinoic acid-inducible gene I (RIG-I) in host cells recognizes viral RNA and activates the expression of type I IFN. To investigate the roles of protein methyltransferases and demethylases in RIG-I antiviral signaling pathway, we screened all the known related enzymes wit...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2021-09-01
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| Serie: | PLoS Pathogens |
| Accesso online: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009918&type=printable |
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