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Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression.

Under RNA virus infection, retinoic acid-inducible gene I (RIG-I) in host cells recognizes viral RNA and activates the expression of type I IFN. To investigate the roles of protein methyltransferases and demethylases in RIG-I antiviral signaling pathway, we screened all the known related enzymes wit...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Qi-Xin Hu, Hui-Yi Wang, Lu Jiang, Chen-Yu Wang, Lin-Gao Ju, Yuan Zhu, Bo Zhong, Min Wu, Zhen Wang, Lian-Yun Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2021-09-01
Rangatū:PLoS Pathogens
Urunga tuihono:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009918&type=printable
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