Notch1 Inhibition Exacerbates APAP-Induced Liver Injury via β-Catenin and Macrophage Polarization

Background: Notch1 signaling regulates innate immune-mediated inflammation in acute liver injury (ALI). However, the precise mechanism by which Notch1 governs macrophage polarization during ALI remains poorly understood. Methods:...

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Autors principals:	Tao Yang, Jingjing Dai, Junlan Zhou, Yuyun Shao, Xiao Wang, Jiaying Zhao, Jun Li, Ping Shi, Longfeng Jiang
Format:	Artigo
Idioma:	Inglês
Publicat:	IMR Press 2025-09-01
Col·lecció:	Frontiers in Bioscience-Landmark
Matèries:	apap β-catenin dapt macrophage notch1 liver inflammation
Accés en línia:	https://www.imrpress.com/journal/FBL/30/9/10.31083/FBL43853
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