Bardoxolone methyl improves survival and reduces clinical measures of kidney injury in tumor-bearing mice treated with cisplatin

Abstract Objective Acute kidney injury (AKI) occurs in approximately one-third of patients treated with cisplatin and there is an outstanding need for mitigation strategies to decrease the frequency and severity of cisplatin-induced AKI. This study evaluated bardoxolone methyl (BARD) as a nephroprot...

Полное описание

Библиографические подробности

Главные авторы:	Lauren E. Thompson, Stacey M. Tuey, Paola Garcia Gonzalez, Carly S. Chesterman, Courtney D. McGinnis, M. Scott Lucia, Lauren M. Aleksunes, Charles L. Edelstein, Melanie S. Joy
Формат:	Artigo
Язык:	Inglês
Опубликовано:	SpringerOpen 2025-03-01
Серии:	AAPS Open
Предметы:	Cisplatin Nephrotoxicity Bardoxolone Methyl Acute Kidney Injury Nrf2
Online-ссылка:	https://doi.org/10.1186/s41120-025-00107-5
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!