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VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals.

Vascular endothelial growth factor A (VEGF-A) plays pivotal roles in regulating tumor angiogenesis as well as physiological vascular function. The major VEGF-A isoforms, VEGF-A121 and VEGF-A165, in serum, plasma, and platelets have not been exactly evaluated due to the lack of the appropriate assay...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Munekazu Yamakuchi, Masashi Okawa, Kazunori Takenouchi, Aryal Bibek, Shingo Yamada, Keiichi Inoue, Kazuhiko Higurashi, Akito Tabaru, Kiyonori Tanoue, Yoko Oyama, Sadayuki Higashi, Chieko Fujisaki, Hideaki Kanda, Hiroto Terasaki, Taiji Sakamoto, Yoshiharu Soga, Teruto Hashiguchi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2023-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0284131
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