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Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control

Abstract Human induced pluripotent stem cells (iPSCs) have great potential in research, but pluripotency testing faces challenges due to non-standardized methods and ambiguous markers. Here, we use long-read nanopore transcriptome sequencing to discover 172 genes linked to cell states not covered by...

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Bibliographic Details
Main Authors: Jochen Dobner, Sebastian Diecke, Jean Krutmann, Alessandro Prigione, Andrea Rossi
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52922-1
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