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Consolidative use of radiotherapy to block oligoprogression in patients with metastatic melanoma on Systemic Therapy (CURB-Melanoma) - a single arm, phase 2 clinical trial

Purpose/objectivePatients with metastatic melanoma on active systemic therapy can develop isolated disease progression while the majority of disease remains controlled (oligoprogression). This phase 2 trial investigates whether stereotactic body radiation therapy (SBRT) or hypofractionated radiation...

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Principais autores: Oded Icht, Alexander Sun, Philip Wong, Andrew McPartlin, Thiago Pimentel Muniz, Anna Spreafico, Samuel D. Saibil, J. Nicholas Lukens, Sana D Karam, John De Almeida, Marcus O. Butler, C. Jillian Tsai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-07-01
coleção:Frontiers in Oncology
Assuntos:
immunotherapy
metastatic melanoma
oligometastatic disease
oligoprogression
SBRT
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2026.1841070/full
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