Consolidative use of radiotherapy to block oligoprogression in patients with metastatic melanoma on Systemic Therapy (CURB-Melanoma) - a single arm, phase 2 clinical trial

Purpose/objectivePatients with metastatic melanoma on active systemic therapy can develop isolated disease progression while the majority of disease remains controlled (oligoprogression). This phase 2 trial investigates whether stereotactic body radiation therapy (SBRT) or hypofractionated radiation...

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Main Authors:	Oded Icht, Alexander Sun, Philip Wong, Andrew McPartlin, Thiago Pimentel Muniz, Anna Spreafico, Samuel D. Saibil, J. Nicholas Lukens, Sana D Karam, John De Almeida, Marcus O. Butler, C. Jillian Tsai
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-07-01
Series:	Frontiers in Oncology
Subjects:	immunotherapy metastatic melanoma oligometastatic disease oligoprogression SBRT
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1841070/full
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