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pH-sensitive micelles self-assembled from star-shaped TPGS copolymers with ortho ester linkages for enhanced MDR reversal and chemotherapy

TPGS approved by FDA can be used as a P-gp inhibitor to effectively reverse multi-drug resistance (MDR) and as an anticancer agent for synergistic antitumor effects. However, the comparatively high critical micelle concentration (CMC), low drug loading (DL) and poor tumor target limit its further cl...

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Detaylı Bibliyografya
Asıl Yazarlar: Yong Xu, Shi Wang, Longshun Yang, Yuhang Dong, Yafang Zhang, Guoqing Yan, Rupei Tang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: KeAi Communications Co., Ltd. 2021-05-01
Seri Bilgileri:Asian Journal of Pharmaceutical Sciences
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S1818087621000143
Etiketler: Etiketle
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