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A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells

Synthetic double-stranded small interfering RNAs (siRNAs) mimic interference RNAs (RNAi) and can bind target mRNAs with a high degree of specificity, leading to selective knockdown of the proteins they encode. However, siRNAs are very labile and must be both protected and transported by nanoparticle...

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Bibliografski detalji
Glavni autori: Cristina de la Torre, Pablo Játiva, Inmaculada Posadas, Darío Manzanares, José L. Jiménez Blanco, Carmen Ortiz Mellet, José Manuel García Fernández, Valentín Ceña
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-11-01
Serija:Pharmaceutics
Teme:
Online pristup:https://www.mdpi.com/1999-4923/14/11/2424
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