TgJosephin and TgRad23 are important for anti-IFN-γ virulence via deubiquitination of SPM1 in Toxoplasma

ABSTRACT Toxoplasma gondii, which can virtually infect all warm-blooded cells, secretes various virulence factors to evade interferon-gamma (IFN-γ)-dependent host immunity. While these secreted proteins are widely characterized, the molecular mechanisms important for virulence within the parasite ar...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Emi Hashizaki, Yuta Tachibana, Junpei Fukumoto, Eizo Takashima, Hidetaka Kosako, Daisuke Okuzaki, Miwa Sasai, Masahiro Yamamoto
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2026-05-01
Schriftenreihe:	mSphere
Schlagworte:	Rad23 ataxin-3 TgJosephin deubiquitinase SPM1 IFN-γ
Online-Zugang:	https://journals.asm.org/doi/10.1128/msphere.00137-26
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!