TgJosephin and TgRad23 are important for anti-IFN-γ virulence via deubiquitination of SPM1 in Toxoplasma

ABSTRACT Toxoplasma gondii, which can virtually infect all warm-blooded cells, secretes various virulence factors to evade interferon-gamma (IFN-γ)-dependent host immunity. While these secreted proteins are widely characterized, the molecular mechanisms important for virulence within the parasite ar...

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Библиографические подробности

Главные авторы:	Emi Hashizaki, Yuta Tachibana, Junpei Fukumoto, Eizo Takashima, Hidetaka Kosako, Daisuke Okuzaki, Miwa Sasai, Masahiro Yamamoto
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology 2026-05-01
Серии:	mSphere
Предметы:	Rad23 ataxin-3 TgJosephin deubiquitinase SPM1 IFN-γ
Online-ссылка:	https://journals.asm.org/doi/10.1128/msphere.00137-26
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