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Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

Abstract Exosomes participate in intercellular communication and glioma microenvironment modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote the generation of the immunosuppressive microenvironment are still unclear. Here, we investigated the effects of GDEs on autop...

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Autori principali: Jianye Xu, Jian Zhang, Zongpu Zhang, Zijie Gao, Yanhua Qi, Wei Qiu, Ziwen Pan, Qindong Guo, Boyan Li, Shulin Zhao, Xiaofan Guo, Mingyu Qian, Zihang Chen, Shaobo Wang, Xiao Gao, Shouji Zhang, Huizhi Wang, Xing Guo, Ping Zhang, Rongrong Zhao, Hao Xue, Gang Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2021-04-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-021-03664-1
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